Department of Biophysics

• Molecular organization & Structural Recognition.
• The structural basis of biological function.
• Crystallographic structure and modeling ofprotease system to understand differential binding affinity, key to specificity in biology specially for protease drug design protocol . Calotropin DII, a thiol Protease, is solved and electron density map & final refinement is completed.
• Co-crystallization and structure elucidation of small model complexes of amino acids and nucleotides in their supramolecular association have been done to understand molecular recognition in biology.
• Difference in cognate/noncognate tRNA - tRNA Synthetase interaction has been linked to a conformational change.
• Molecular basis of cooperativity in l-repressor operator system
• Development of a model for protein electron transfer.
• Installation of a functional 500 MHz FT-NMR Spectrometer for various structural work.

Animal Physiology Department Department of Biochemistry Department of Biophysics Department of Botany Department of Chemistry Department of Immunology and Molecular Biology Department of Microbiology Department of Physics Department of Plant Molecular and Cellular Genetics Workshop of Bose Institute